The ergogenic ability of hydrogen administration is demonstrated in a number of recent studies by defining the mechanism of action by which molecular hydrogen has the abilities to stimulate energy production.

At least two complementary mechanisms have been identified: induction of the protein called Mitochondrial unfolded protein response (the mtUPR) and increased activity of the mitochondrial ETC (Electron Transport Chain).

Thus, molecular hydrogen manages mitochondrial stress through mtUPR activation and exerts its effects on diseases such as chronic fatigue, Parkinson’s disease, myocardial or cerebral infarction, and inflammatory diseases related to oxidative stress.

In the findings reported by Blue Hydrogen Science in a recent Observational Study, users undergoing percutaneous hydrogen therapy not only benefit from a Detox effect, but also benefit from increased muscle energy and physical strength at the end of each treatment.

There are, in addition, Studies Associated with the use of Hydrogen concerning the recovery of fatigue (sense of chronic fatigue) in POST COVID-2 and LONG COVID Syndrome.